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Characterization of a novel live attenuated infectious bronchitis virus vaccine candidate derived from a Korean nephropathogenic strain

✍ Scribed by Hyun Jeong Lee; Ha Na Youn; Ji Sun Kwon; Youn Jeong Lee; Jae Hong Kim; Joong Bok Lee; Seung Yong Park; In Soo Choi; Chang Seon Song


Book ID
116962430
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
198 KB
Volume
28
Category
Article
ISSN
0264-410X

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## Abstract A temperature‐sensitive mutant virus unable to replicate at 38°C was recovered from passage 189 (IVpi‐189) of Madin‐Darby canine kidney cells infected persistently with influenza A. Immunofluorescent staining of the IVpi‐189 virus‐infected cells revealed disrupted transport of the matri