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Characterization of a human osteoblastic osteosarcoma cell line (SAOS-2) with high bone alkaline phosphatase activity

✍ Scribed by Elsa Murray; Diego Provvedini; Deborah Curran; Bayard Catherwood; Howard Sussman; Stavros Manolagas


Book ID
112118252
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
620 KB
Volume
2
Category
Article
ISSN
0884-0431

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Estrogen inhibits interleukin-6 producti
✍ Moustapha Kassem; Steven A. Harris; Thomas C. Spelsberg; B. Lawrence Riggs πŸ“‚ Article πŸ“… 2009 πŸ› American Society for Bone and Mineral Research 🌐 English βš– 848 KB

Some studies suggest that estrogen acts on bone by decreasing the production of interleukin-6 (IL-6), a cytokine that increases bone resorption, by osteoblasts or bone marrow cells. However, other studies have not confirmed this, possibly because of a low and variable number of estrogen receptors (E