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Characterization of a glycopeptide from pathological human IgM with an unusual oligosaccharide core

✍ Scribed by Jacqueline Jouanneau; Roland Bourrillon


Book ID
118314107
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
308 KB
Volume
91
Category
Article
ISSN
0006-291X

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## Abstract Using X‐ray crystallography, a human monoclonal IgM cryoglobulin (Mez) was found to have an unusual combining site topography. Analysis of the unliganded Fv at 2.6β€…Γ… resolution revealed that the HCDR3 had partitioned the active site into two compartments [Ramsland PA __et al.__ 2000. __