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Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase μ

✍ Scribed by Julie K Horton; Gargi Roy; John T Piper; Bennett Van Houten; Yogesh C Awasthi; Sankar Mitra; Moulay A Alaoui-Jamali; Istvan Boldogh; Sharad S Singhal


Book ID
113994480
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
386 KB
Volume
58
Category
Article
ISSN
0006-2952

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Glutathione transferases (GSTs) have been shown to be overexpressed in a number of tumor cell lines selected for resistance to chemotherapeutic drugs and have been implicated in some studies of clinical specimens. In tumor cell lines selected for resistance to chemicals that alkylate DNA, the isofor