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Characterization, Mapping, and Expression of the Human Ceruloplasmin Gene

โœ Scribed by Funmei Yang, Susan L. Naylor, Jean B. Lum, Stephen Cutshaw, Jerome L. McCombs, Kathleen H. Naberhaus, John R. McGill, Gwen S. Adrian, Charleen M. Moore, Don R. Barnett and Barbara H. Bowman


Book ID
123632821
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
1001 KB
Volume
83
Category
Article
ISSN
0027-8424

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Human ceruloplasmin, which is usually cleaved by limited proteolysis into three major fragments during preparation (M, = 18,650,5O,OOO, and 70,OOO) was isolated in good yield as an undegraded single-chain protein (M, = 135,000). The cryosupernatant from fresh frozen plasma (100 liters) was fractiona