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Characterization and use of laser-based lysis for cell analysis on-chip

✍ Scribed by Lai, H.-H.; Quinto-Su, P. A; Sims, C. E; Bachman, M.; Li, G.P; Venugopalan, V.; Allbritton, N. L

Book ID
120122737
Publisher
The Royal Society
Year
2008
Tongue
English
Weight
330 KB
Volume
5
Category
Article
ISSN
1742-5689

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## Abstract We have developed an on‐chip single‐cell based microcultivation method for analyzing the variability of genetic information stored in single cells and their epigenetic correlations. The method uses four systems: an on‐chip cell sorter for purifying the cells in a non‐destructive manner;