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Characterization and regulation of the vitamin D hydroxylases

✍ Scribed by Armbrecht, H.James; Okuda, Kyuichiro; Wongsurawat, N.; Nemani, Rama K.; Chen, Ming L.; Boltz, Monica A.

Book ID
122782226
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
871 KB
Volume
43
Category
Article
ISSN
0960-0760

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πŸ“œ SIMILAR VOLUMES

Vitamin D hydroxylases
Vitamin D hydroxylases
✍ Helen L. Henry πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 510 KB

## Abstract There are three mixed function oxidases which catalyze hydroxylations of vitamin D and its derivatives. These include the hepatic mitochondrial or microsomal vitamin D~3~‐25‐hydroxylase and the two renal mitochondrial enzymes which further hydroxylate 25‐hydroxyvitamin‐D~3~ (25‐OH‐D~3~)

Inhibitors of vitamin D hydroxylases: St
Inhibitors of vitamin D hydroxylases: Structure–activity relationships
✍ Inge Schuster; Helmut Egger; Peter Nussbaumer; Romano T. Kroemer πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 309 KB

## Abstract Aiming at new drugs to efficiently treat diseases, in which either increased or decreased levels of active vitamin D are desirable, we have designed some 400 structurally different azole‐type inhibitors and examined their capacity to selectively block vitamin D metabolism by CYP24 or sy