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Characterization and Proteome Analysis of Inosine 5-Monophosphate Dehydrogenase in EpidemicStreptococcus suisSerotype 2

✍ Scribed by Zhou, Junming; Zhang, Xuehan; He, Kongwang; Wang, Wei; Ni, Yanxiu; Zhu, Haodan; Yu, Zhengyu; Mao, Aihua; Lv, Lixin


Book ID
121535638
Publisher
Springer
Year
2014
Tongue
English
Weight
305 KB
Volume
68
Category
Article
ISSN
0343-8651

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Antiproliferative effects of AVN944, a n
✍ Daniel Floryk; Timothy C. Thompson πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 French βš– 384 KB

## Abstract Inosine 5‐monophosphate dehydrogenase II, a key enzyme in the __de novo__ synthesis of purine nucleotides, is expressed in prostate tumors and prostate cancer cells. AVN944 is a new, specific, noncompetitive IMPDH inhibitor. In this study, we investigated the effects of IMPDH inhibitor