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Characterization and pH-dependent substrate specificity of alkalophilic xylanase fromBacillus alcalophilus

✍ Scribed by Dae-Seok Lee, Kwang-Ho Lee, Eun-Jin Cho, Ho Myeong Kim, Chang-Sook Kim, Hyeun-Jong Bae

Book ID
118793203
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
749 KB
Volume
39
Category
Article
ISSN
1476-5535

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## Abstract Cathepsin B is a cysteine protease that in tumor tissues is localized in both acidic lysosomes and extracellular spaces. It can catalyze the cleavage of peptide bonds by two mechanisms: endoproteolytic attack with a pH optimum around 7.4, and attack from the __C__‐terminus with a pH opt