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Characterization and meiotic segregation of a supernumerary marker chromosome in sperm of infertile males: Case report and literature review

✍ Scribed by Perrin, Aurore; Nguyen, Ming Huong; Delobel, Bruno; Guéganic, Nadia; Basinko, Audrey; Le Bris, Marie-Josée; Douet-Guilbert, Nathalie; De Braekeleer, Marc; Morel, Frédéric

Book ID
120059181
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
262 KB
Volume
55
Category
Article
ISSN
1769-7212

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The frequencies of aneuploid and diploid sperm were determined in a 47,XYY male using multi-color fluorescence in situ hybridization (FISH) analysis, and compared with those from 10 control donors. A total of 30,078 sperm from the patient was scored, 15,044 by two-color FISH for chromosomes 13 and 2