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Characterization and Mapping of a B-Cell Immunogenic Domain in Hepatitis C Virus E2 Glycoprotein Using a Yeast Peptide Library

✍ Scribed by Michael A. Mink; Serge Benichou; Pascal Madaule; Pierre Tiollais; Alfred M. Prince; Genevieve Inchauspe


Book ID
112269672
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
599 KB
Volume
200
Category
Article
ISSN
0042-6822

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A peptide mimotope of hepatitis C virus
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## Abstract Conformational B‐cell epitopes on the HCV E2 protein recognized by human antibodies were characterized by the use of a peptide mimotope named K1. K1 was identified by two HCV anti‐E2 monoclonal antibodies (mAbs) following selection and purification of phage clones containing a 15‐mer ra