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Characterization and differentiation potential of rat ventral mesencephalic neuronal progenitor cells immortalized with SV40 large T antigen

✍ Scribed by André Nobre; Ieva Kalve; Konstantin Cesnulevicius; Daniela Rangancokova; Andreas Ratzka; Nina Halfer; Maike Wesemann; Klaus Krampfl; Peter Claus; Claudia Grothe


Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
892 KB
Volume
340
Category
Article
ISSN
0302-766X

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## Abstract To understand the characteristics of tsAM5D cells immortalized with the temperature‐sensitive simian virus 40 large T‐antigen, we first examined the responsiveness of the cells to ligands of the glial cell line‐derived neurotrophic factor (GDNF) family. tsAM5D cells proliferated at the