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Characterization and Crystallization of Recombinant Human Cathepsin L

✍ Scribed by Toshiyuki Nomura; Akira Fujishima; Yukio Fujisawa


Book ID
115579392
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
215 KB
Volume
228
Category
Article
ISSN
0006-291X

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## Abstract We have expressed active human cathepsin S to 60 mg/L in Sf9 cells using a baculovirus system. Production of milligram quantities has facilitated crystallographic studies to determine the structure of this enzyme, which has unique properties among lysosomal cysteine proteinases. Recombi