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Characterization and comparison of diblock and triblock amphiphilic copolymers of poly(δ-valerolactone)

✍ Scribed by Wen-Jen Lin; Chia-Ling Wang; Lee-Wei Juang

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
131 KB
Volume
100
Category
Article
ISSN
0021-8995

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Nanoparticles with the dimensions of circa 50 nm prepared from the micellar aggregation of diblock copolymers of poly(ethylene oxide) and polycaprolactone (PEO-b-PCL) were explored as a parenteral carrier system for water-soluble organic drugs in salt form. Enalapril maleate (EPM), developed for hyp