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Characteristics of specific in vivo labeling of neuroleptic binding sites with 3-N-[11C]methylspiperone

✍ Scribed by Kazuhiko Yanai; Tatsuo Ido; Kiichi Ishiwata; Jun Hatazawa; Shoichi Watanuki; Toshihiro Takahashi; Akira Ujiie; Masatoshi Ito; Taiju Matsuzawa


Book ID
104688860
Publisher
Springer
Year
1986
Tongue
English
Weight
595 KB
Volume
11
Category
Article
ISSN
0340-6997

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Production of 3-N-[11C]methylspiperone w
✍ Kazutoshi Suzuki; Osamu Inoue; Kazuhiko Tamate; Fujio Mikado πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science βš– 699 KB

3-N-[11C]methylspiperone(11C-NMS, molecular weight = 409 for 12C-NMS) has been prepared automatically with high specific activity (37 +/- 18 GBq/mumol at EOS) for the measurement of dopamine D2 receptors in the human brain with a positron camera. It was observed that the radiochemical purity of 11C-