Characteristics of hyperthermia and its complications in patients with Prader Willi syndrome
✍ Scribed by Erdal Ince; Ergin Çiftçi; Mustafa Tekin; TanIl Kendirli; Ercan Tutar; Nazan DalgIç; Selim Öncel; Ülker Dogru
- Book ID
- 108971049
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 135 KB
- Volume
- 47
- Category
- Article
- ISSN
- 1328-8067
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Prader-Willi syndrome (PWS) is a genomic imprinting disorder, which is due to the loss of a functional paternal copy of 15q11-q13. Four different genetic mechanisms can lead to PWS: a paternal deletion of the 15q11-q13 region, maternal uniparental disomy (UPD), a defect in the imprinting center, or
## Abstract Growth hormone (GH) therapy for short stature in patients with Prader–Willi syndrome (PWS) has started worldwide, and various favorable effects have been reported. However, the possibility of progression of scoliosis arises as a new problem of the GH therapy. In this study, we analyzed