Characteristic of the Silencer Located in the CpG-Rich Region Upstream of the Cluster of Chicken α-Globin Genes
✍ Scribed by D. B. Klochkov; E. S. Ioudinkova; S. V. Razin
- Book ID
- 111579507
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2004
- Tongue
- English
- Weight
- 61 KB
- Volume
- 398
- Category
- Article
- ISSN
- 1607-6729
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The globin gene clusters of Xenopus laevis are interspersed by various different repetitive DNA elements. A specific repeat, the JH12 element, has been mapped by Southern analysis and some of its locations have been subsequently confirmed by nucleotide sequencing. JH12 family members seem to represe
## Abstract Switching in hemoglobin gene expression is an informative paradigm for studying transcriptional regulation. Here we determined the patterns of chicken α‐globin gene expression during development and erythroid differentiation. Previously published data suggested that the promoter regions