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Characteristic of immobilized cephalosporin C acylase and its application in one-step enzymatic conversion of cephalosporin C to 7-aminocephalosporanic acid

✍ Scribed by Xiangwei Zhu; Hui Luo; Yanhong Chang; Houbo Su; Qiang Li; Huimin Yu; Zhongyao Shen

Publisher
Springer
Year
2010
Tongue
English
Weight
279 KB
Volume
27
Category
Article
ISSN
1573-0972

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## Abstract The main drawback in the production of 7‐aminocephalosporanic acid (7‐ACA) at the industrial level is the inactivation of the enzymes implicated in the process due to the presence of hydrogen peroxide during the reaction. As an alternative, we have developed the conversion of cephalospo