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Characteristic expression of extracellular matrix metalloproteinase inducer (CD147/EMMPRIN) in human endometrium during menstrual cycle

โœ Scribed by Tetsuaki Hara; Takashi Sato; Yutaka Noguchi; Koso Ohama; Michiko Hirata; Akira Ito

Book ID
119421072
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
17 KB
Volume
80
Category
Article
ISSN
1556-5653

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EMMPRIN (extracellular matrix metalloproteinase inducer), also called CD147, basigin or M6 in the human, is a member of the immunoglobulin superfamily that is present on the surface of tumor cells and stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPs). In our study, we inves

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## Background: Matrix metalloproteinases (mmps) contribute to matrix remodelling in venous leg ulcers. extracellular mmp inducer (emmprin; cd147) has been reported to increase mmp expression, and membrane type 1 mmp (mt1-mmp) has been implicated in the activation of mmps. ## Objectives: To examin