DNA sequence analysis of spontaneous hpr
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P. R. Harbach; S. S. Mattano; D. M. Zimmer; Y. Wang; C. S. Aaron
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Article
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1995
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John Wiley and Sons
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English
β 683 KB
To study the mechanisms of mutagenesis in vivo, we analyzed mutations at the hypoxanthine phosphoribosyl transferase (hprf) locus using cDNA from cynomolgus monkey T-lymphocytes. In the present study, the spectrum of spontaneous hprt mutations arising in vivo in wildcaught cynomolgus monkey peripher