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Characterisation of the T cell and dendritic cell repertoire in a murine model of mucopolysaccharidosis I (MPS I)

✍ Scribed by Louise D Archer,Kia J Langford-Smith…

Book ID: 126350808
Publisher: Springer
Year: 2012
Tongue: English
Weight: 218 KB
Volume: 36
Category: Article
ISSN: 0141-8955
DOI: 10.1007/s10545-012-9508-8

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## Abstract ## Objective To explore the role of immune cells in anti‐RNP autoimmunity in a murine model of pneumonitis or glomerulonephritis, using adoptive transfer techniques. ## Methods Donor mice were immunized with 50 μg of U1–70‐kd small nuclear RNP fusion protein and 50 μg of U1 RNA adjuv