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Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire

✍ Scribed by Judith Boffey; Masaaki Odaka; Dawn Nicoll; Eric R. Wagner; Kate Townson; Tyrone Bowes; Joe Conner; Koichi Furukawa; Hugh J. Willison


Book ID
113729605
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
532 KB
Volume
165
Category
Article
ISSN
0165-5728

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Regulation of immunoglobulin variable re
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The immune system can generate an almost infinite number of direrent antibody specificities, the s u m of which is the antibody repertoire. This article con- siders aspects of the mechanism and control of immunoglobulin variable ( V ) region gene assembly with a focus on how these factors may afect