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Characterisation of the H295R adrenocortical cell line as potential endocrine disrupter screening system using a toxicogenomics approach

✍ Scribed by Caroline Vanparys; Marleen Maras; Koen Van Leemput; Karlijn van der Ven; Johan Robbens; Ronny Blust; Wim De Coen

Book ID
119379552
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
81 KB
Volume
172
Category
Article
ISSN
0378-4274

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## Abstract The adrenal gland is a vulnerable target for toxic insult. Disruption of adrenal steroidogenesis and hormone secretion may cause serious effects on human health. A human __in vitro__ model is needed to predict effects, and elucidate mechanisms of endocrine disruption and adrenal toxicit