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Characterisation of tachykinin receptors using selectivity of agonists and antagonists: Evidence for an NK-4 type

โœ Scribed by A.T. McKnight; J.J. Maguire; M.A. Varney; B.J. Williams; L.L. Iversen


Book ID
118398268
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
52 KB
Volume
22
Category
Article
ISSN
0167-0115

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Use of Selective Agonists and Antagonist
โœ L. Yuan; E. Burcher; B.S. Nail ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier ๐ŸŒ English โš– 426 KB

SUMMARY: Tachykinins are potent bronchoconstrictors. Here we have used novel highly selective agonists and antagonists to characterize tachykinin receptors mediating bronchoconstriction and hypotension in anaesthetized, paralysed guinea-pigs. Total lung resistance \(\left(R_{L}\right)\) and dynamic