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Characterisation of cisplatin coordination sites in cellularEscherichia coliDNA-binding proteins by combined biphasic liquid chromatography and ESI tandem mass spectrometry

✍ Scribed by Joanna Will; William S. Sheldrick; Dirk Wolters


Book ID
106232169
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
654 KB
Volume
13
Category
Article
ISSN
1432-1327

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Characterisation of Cisplatin Binding Si
✍ Joanna Will; Dirk A. Wolters; William S. Sheldrick 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 833 KB

## Abstract Cisplatin binding sites in human serum proteins have been characterised by using combined multidimensional liquid chromatography and ESI tandem mass spectrometry (MudPIT). Following incubation periods of 3 h for cisplatin–blood serum mixtures and subsequent trypsin digestion, MS–MS spec