Fibril aggregation inhibitory activity o
Fibril aggregation inhibitory activity of the β-sheet breaker peptides: a molecular docking approach
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Maria Giovanna Chini; Mario Scrima; Anna Maria D'Ursi; Giuseppe Bifulco
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Article
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2009
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John Wiley and Sons
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English
⚖ 324 KB
## Abstract In the present study, we used a molecular docking as a rapid, interactive method to study the inhibition of fibrillogenesis process by β‐sheet breaker peptide (BSB) (Ac‐L^1^‐V^2^‐(NMet)F^3^‐F^4^‐A^5^‐NH~2~). Our aim was to find the complex (Aβ:BSB) that blocks the aggregation of the fib