Changing Patterns of Spontaneous Bursting Activity of On and Off Retinal Ganglion Cells during Development
โ Scribed by R.O.L Wong; D.M Oakley
- Book ID
- 117606744
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 218 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0896-6273
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Anatomical and physiological segregation of neurons into ON (brightening detector) and OFF (darkening detector) channels in the retina and subsequent visual system ensure the high sensitivity required for contrast detection and spatial discrimination. This segregation 9 is finest at the visual axis.
The effect of LSD 25 (i. v. injection) on the spontaneous and evoked activity of the visual system was investigated in cats. 50 y/kg did not change significantly the ERG and the visual cortical evoked potential. The spontaneous discharge rate of 14 out of 21 retinal ganglion cells showed an increase