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Changes of the genome DNA methylation in the progress of benzo[a]pyrene-induced transformation

✍ Scribed by L. Yang; G. Tao; C. Gong; L. Zhou; J. Liu; Z. Zhuang


Book ID
116923222
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
72 KB
Volume
196
Category
Article
ISSN
0378-4274

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## Abstract A study of the liver microsome‐mediated binding to added DNA of the phenol metabolites of benzo (a)‐pyrene (BP‐OH) and of 7,8‐dihydro‐7,8‐dihydroxybenzo (a)pyrene (BP‐7,8‐diol) suggested that as in the case of BP itself the reaction was catalysed by the enzyme aryl hydrocarbon hydroxyla