Changes of pH and counterion activity during the binding process of cationic surfactants to carboxylic polyions

Use of Factorial Experimental Design to

Use of Factorial Experimental Design to Delineate the Strong Calcium- and pH-Dependent Changes in Binding of Human Surfactant Protein-A to Neutral Glycosphingolipids-A Model for Studies of Protein-Carbohydrate Interactions

✍ L. Hynsjo; L. Granberg; J. Haurum; S. Thiel; G. Larson 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 821 KB

Human surfactant protein-A (SP-A) is a C-type lectin belonging to the collection supergroup of mammalian lectins. It is produced by alveolar type II cells and has been shown to bind to lactosylceramide (R. A. Childs, J. R. Wright, G. F. Ross, C-T Yuen, A. M. Lawson, C. Chai, K. Drickamer, and T. Fei