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Changes of biological markers and brain PET imaging and clinical effects of memantine for patients with moderate to severe Alzheimer's disease: A 24-week double-blind, randomized, placebo-controlled study

✍ Scribed by Shifu Xiao; Tao Wang; Qiu Huang; Kewei Chen; Eric Reiman

Book ID: 118467719
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 52 KB
Volume: 7
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2011.05.866

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## Abstract ## Objectives The post‐hoc analyses reported here evaluate the specific effects of memantine treatment on ADAS‐cog single‐items or SIB subscales for patients with moderate to severe AD. ## Methods Data from six multicentre, randomised, placebo‐controlled, parallel‐group, double‐blind