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Changes in α1-adrenergic vascular reactivity in monocrotaline-treated rats

✍ Scribed by Stefan Dhein; Christine Giessler; Ingrid Heinroth-Hoffmann; Kirsten Leineweber; Torsten Seyfarth; Otto-Erich Brodde

Book ID
105876034
Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
251 KB
Volume
365
Category
Article
ISSN
0028-1298

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We recently reported that platelet-activating factor (PAF) levels increased in lung tissue after 1 subcutaneous injection of monocrotaline (MCT) (which causes lung injury), and, further, that treatment with PAF antagonists reduced pulmonary hypertension in this chronic lung injury rat model [15]. In