Changes in Tissue Metalloproteinase Inhibitor-1 and Matrix Metalloproteinases during Tumor Development and Metastasizing in Mice
โ Scribed by T. A. Korolenko; T. G. Filatova; V. M. Belichenko; T. V. Alexeenko; S. Ya. Zhanaeva
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 394 KB
- Volume
- 150
- Category
- Article
- ISSN
- 0007-4888
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We analyzed blood plasma concentrations of matrix metalloproteinase-1 and -3 (MMP-1; MMP-3), the tissue inhibitor of metalloproteinase-1 (TIMP-1) and the complex MMP-1/ TIMP-1, and looked for any correlation with prostate cancer stage. These components were measured by ELISA tests specific for these
## Background: The balance between matrix metalloproteinases (mmp) and the tissue inhibitors of metalloproteinases (timp) has been seen as important during tumor invasion and progression. the determination of these components needs a special strategy of tissue preparation. this analytical problem h