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Changes in the surface marker pattern related to maturation in adult acute myeloid leukaemia

✍ Scribed by Dick J. van Rhenen; Hendrik J. van der Reijden; Mars B. van 't Veer; C.Paul Engelfriet; Albert E.G.Kr. von dem Borne; Mart M.A.C. Langenhuijsen


Book ID
113238229
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
393 KB
Volume
7
Category
Article
ISSN
0145-2126

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## Abstract Cytogenetic abnormalities are among the most important factors affecting the outcome of patients with acute myeloid leukaemia (AML), but approximately 40–50% of AML cases display a normal karyotype at diagnosis. Multidrug resistance (MDR) proteins overexpression is associated with worse