Changes in the strength characteristics of human intervertebral disks under compression
โ Scribed by V. I. Danilov
- Publisher
- Springer US
- Year
- 1977
- Tongue
- English
- Weight
- 705 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1573-8922
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While in vitro studies have shown that mechanical loading can result in changes in the composition of intervertebral disc matrix, the effects of cyclic loading in vivo have not been considered. The objective of this study was to assess the effect of static and cyclic compression of different frequen
## Abstract Intervertebral disc degeneration (IDD) pertains to the loss of extracellular matrix (ECM), particularly the early loss of aggrecan, the turnover of which is regulated by ADAMTSs. Amongst the etiological factors of IDD, mechanical stress plays an important role in the physiological and p