Changes in the polyelectrolyte-amphiphile interaction due to helix-coil transition induced by specific counterions or variations in temperature
✍ Scribed by Ninus Caram-Lelham; Lars-Olof Sundelöf
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1998
- Tongue
- English
- Weight
- 548 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0006-3525
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✦ Synopsis
For the system K-carrageenan/amitriptyline it is shown that the degree of binding of amitriptyline is closely related to the currageenan conformation as regulated by the counterions (Nu+ or K+). The adsorption becomes much more pronounced when the carrageenan molecule is in the helix form (counterion K+) than when it has a coil conformation (counterion Nu+). Furthermore, for the helical state the adsorption becomes strong1.v cooperative. It is also shown experimentally that the release from the adsorbed state has a conversion temperature at about 42°C (helix-coil transition). The effect is also related to the linear charge density. For 1-carrageenan with a higher charge density the adsorption is strong and cooperative both in the presence of Nu+ and K+ ions.