## Abstract Excessive immune activation is a hallmark of chronic uncontrolled HIV infection. During the past years, growing evidence suggests that immune inhibitory signals also play an important role in progressive disease. However, the relationship between positive and negative immune signals on
Changes in the level of apoptosis-related proteins in Jurkat cells infected with HIV-1 versus HIV-2
β Scribed by Xue Wang; Ragupathy Viswanath; Jiangqin Zhao; Shixing Tang; Indira Hewlett
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 426 KB
- Volume
- 337
- Category
- Article
- ISSN
- 0300-8177
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Peripheral blood lymphocytes (PBLs) from 51 HIV-1-seropositive subjects with different levels of HIV-1 replication and 20 healthy blood donors were examined for the expression of the antiapoptotic Bcl-2 protein. All the plasma samples from HIV-1 patients were characterized for the presence of HIV-1
## Abstract Heat shock proteins (Hsp), especially 70 kDa heat shock protein (Hsp70) play an important role in the life cycle of HIVβ1 virus. Hsp70 is overexpressed in HIVβinfected cells and this is the most abundant Hsp associated with HIV virions. The aim of our study was to investigate whether HI