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Changes in the functional activity of membrane-bound guanylate cyclase forms in tissues of diabetic rats

✍ Scribed by A. O. Shpakov; K. V. Derkach; O. V. Chistyakova; M. N. Pertseva


Book ID
111470111
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
120 KB
Volume
433
Category
Article
ISSN
1607-6729

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Glibenclamide enhanced the activity in the rat of guanylate cyclase in a number of extra-pancreatic tissues. Thus, glibenclamide enhanced guanylate cyclase activity in vitro two- to threefold in liver, kidney, heart, spleen and colon at a concentration of 1 mumol/l. Dose-response curves of glibencla