## Abstract ## BACKGROUND Although various mechanisms have been recognized as being associated with the development of resistance to imatinib mesylate in vitro and in clinical situations, their relative significance and contributions remain poorly understood, as is the sequence of events leading t
✦ LIBER ✦
Changes in the expression of proteins associated with aerobic glycolysis and cell migration are involved in tumorigenic ability of two glioma cell lines
✍ Scribed by Anelisa Ramão, Marcela Gimenez, Helen Julie Laure, Clarice Izumi, Rodrigo Cesar dos Santos Vida, Sueli Oba-Shinjo, Suely Kazue Nagahashi Marie, Jose Cesar Rosa
- Book ID
- 119902207
- Publisher
- BioMed Central
- Year
- 2012
- Tongue
- English
- Weight
- 528 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1477-5956
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## Abstract Small cell lung cancer (SCLC) initially responds well to DNA damaging drugs such as cisplatin, however this is transitory as resistance normally develops. To investigate whether changes in chromosomal copy number caused by platinum drug treatment contributes to platinum resistance, we h