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Changes in the expression of class I major histocompatibility complex antigen RNA induced by interferon in rat hepatoma cells

✍ Scribed by Scott, R.J.; Hammons, K.V.; Hunt, J.M.


Book ID
125438226
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
992 KB
Volume
50
Category
Article
ISSN
0304-3835

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Mouse embryonal carcinoma F9 cells, upon treatment with interferons (IFNs), express major histocompatibility (MHC) Class I antigens, which are otherwise not expressed in these cells. Both I F N y and IFN-aIP increase the steady-state level of Class I mRNA within 60 min of the treatment which leads t