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Changes in the DNA of lymphocytes from pristance treated rats

✍ Scribed by L. R. Garrett; K. L. Bost; T. M. Buttke; M. A. Cuchens


Publisher
SP Birkhäuser Verlag Basel
Year
1987
Tongue
English
Weight
743 KB
Volume
20
Category
Article
ISSN
1420-908X

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Treatment of female SpragueDawley rats with the potent mammary gland carcinogen 7,12dimethyC benz[a]anthracene (DMBA) results in the formation of DNA adducts with dG and dA and in the induction of 6thioguanineresistant (TG') lymphocyte mutants. In this study, we have examined the types of mutations