DNA sequence analysis of hprt mutations
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Robert H. Heflich; Roberta A. Mittelstaedt; Mugimane G. Manjanatha; Lascelles E.
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Article
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1996
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John Wiley and Sons
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English
⚖ 799 KB
Treatment of female SpragueDawley rats with the potent mammary gland carcinogen 7,12dimethyC benz[a]anthracene (DMBA) results in the formation of DNA adducts with dG and dA and in the induction of 6thioguanineresistant (TG') lymphocyte mutants. In this study, we have examined the types of mutations