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Changes in the distribution of fibroblast growth factor in the teleostean testis during spermatogenesis

✍ Scribed by Watanabe, Akihiko ;Onitake, Kazuo

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
943 KB
Volume
272
Category
Article
ISSN
0022-104X

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✦ Synopsis

Abstract

The distribution of fibroblast growth factor (FGF) in the testes of Salvelinus leucomaenis and Oryzias latipes was investigated by immunofluorescence staining. In S. leucomaenis, spermatogonia were strongly stained in the infantile testis. When human chorionic gonadotrophin (HCG) was injected into individual fish, the uptake of 5‐bromo 2′‐deoxyuridine (BrdU) occurred within a day. At the same time, FGF became undetectable in spermatogonia, but appeared for the first time around the testicular somatic cells. A similar distribution was seen in the mature testes of S. leucomaenis and O. latipes. The positively immunostained area corresponded to the predominant site of the Sertoli cells. This pattern of distribution of FGF suggests that FGF plays an important role in the initiation and progression of spermatogenesis in the teleostean testis. © 1995 Wiley‐Liss, Inc.

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