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Changes in the concentration of ions during senescence of the human erythrocyte.

✍ Scribed by Ivan L. Cameron; W.Elaine Hardman; Nancy K.R. Smith; Gary D. Fullerton; Attila Miseta


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
305 KB
Volume
17
Category
Article
ISSN
1065-6995

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✦ Synopsis


Abstract

Flash frozen samples of normal human blood were cryosectioned and cryodried for electron probe x‐ray microanalysis of the concentration of ions and elements in individual erythrocytes (RBCs). The data (expressed in mM/kg dry weight) demonstrated a systematic pattern of variation between the concentration of ions and elements in the RBCs. Specifically as K^+^ and Cl decreased in concentration, Ca^2+^ and sulfur increased in concentration. Phosphorous, Na^+^ and Mg^2+^ did not demonstrate a significant pattern of change. These findings are related to the dehydration and to the volume decrease that accompanies senescence of the RBC.


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