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Changes in Telomerase Activity and Telomere Length during Human T Lymphocyte Senescence

✍ Scribed by Chongxian Pan; Bao-Hua Xue; Thomas M. Ellis; David J. Peace; Manuel O. Dı́az

Book ID
115602629
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
343 KB
Volume
231
Category
Article
ISSN
0014-4827

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## BACKGROUND. Telomeres shorten with successive cell divisions in normal somatic cells. Telomerase is a ribonucleoprotein enzyme associated with cellular proliferation and plays an important role in maintaining the stability of chromosomes and the length of DNA telomeres. Telomerase activity has