The zone of calcified cartilage (ZCC) forms an important interface between cartilage and bone for transmitting force, attaching cartilage to bone, and limiting diffusion from bone to the deeper layers of cartilage. The height of the ZCC is a relatively constant percent of articular cartilage and the
Changes in subchondral bone early in the development of osteoarthritis
β Scribed by S. C. Mastbergen; F. P. J. G. Lafeber
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 35 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To evaluate the relationships among cartilage and subchondral bone before and after the onset of cartilage degeneration in the Hartley guinea pig model of spontaneous osteoarthritis (OA) as compared with those in WeiserβMaple guinea pigs, which do not develop OA. ## Metho
In the recent study by Wang et al (1), the authors concluded that after anterior cruciate ligament transection (ACLT), changes in subchondral bone begin early and simultaneously with cartilage degradation and that oral glucosamine hydrochloride has a protective effect (1). They based this conclusion