Erythrocytes from diabetic patients before and after treatment with the aldose reductase inhibitor, sorbinil, were analyzed by a capillary gas chromatographic method for sorbitol and myo-inositol. The mean erythrocyte sorbitol level in the diabetic patients was significantly higher than in the contr
โฆ LIBER โฆ
Changes in sorbitol,myo-inositol and lipid inositol in dorsal root and sympathetic ganglia from streptozotocin-diabetic rats
โ Scribed by J. G. Llewelyn; C. M. F. Simpson; P. K. Thomas; R. H. M. King; J. N. Hawthorne
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 622 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0012-186X
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A possible relationship between increased sorbitol concentration and decreased myo-inositol concentration in peripheral nerves of diabetic rats has been examined. To this end, sorbinil, an aldose reductase inhibitor, was used either to prevent or reverse elevation of nerve sorbitol concentration in