Changes in sleep after acute and repeated administration of nicotine in the rat
β Scribed by Rafael J. Salin-Pascual; Maria Luisa Moro-Lopez; Hector Gonzalez-Sanchez; Carlos Blanco-Centurion
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 281 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
To identify neuroanatomical substrates affected by nicotine, we have studied its effects after acute and repeated administration through the c-Fos protein inducibility in various brain structures. Ninety minutes after acute nicotine (0.35 mg/kg, sc.) the number of c-Fos-like immunoreactive nuclei wa
Seven-hour sleep EEG recordings were obtained from rats (N = 15) given a single acute dose, and rats (N = 15) given 14 daily doses of zimelidine, 20 mg/kg IP. REM latency, REM sleep, number of REM episodes, and total sleep time were significantly affected by zimelidine administration when compared t