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Changes in sensitivity to radiation and to bleomycin occurring during the life history of monolayer cultures of a mouse tumour cell line

โœ Scribed by Twentyman, P R; Bleehen, N M


Book ID
109833482
Publisher
Nature Publishing Group
Year
1975
Tongue
English
Weight
771 KB
Volume
31
Category
Article
ISSN
0007-0920

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## Abstract The __TP53__ tumor suppressor gene is the most frequently inactivated gene in human cancer identified to date. However, __TP53__ mutations are rare in human mesotheliomas, as well as in many other types of cancer, suggesting that aberrant __TP53__ function may be due to alterations in i