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Changes in protein kinase C activity are associated with the differentiation of Friend erythroleukemia cells

✍ Scribed by Kenneth J. Balazovich; Douglas Portnow; Laurence A. Boxer; Edward V. Prochownik

Book ID
119120548
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
696 KB
Volume
927
Category
Article
ISSN
0167-4889

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## Abstract Friend erythroleukemia cells require high doses (15 Gy) of ionizing radiation to display a reduced rate of proliferation and an increased number of dead cells. Since ionizing radiation can activate several signaling pathways at the plasma membrane which can lead to the nuclear transloca