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Changes in pediatric toxic dose of acetaminophen

✍ Scribed by Guillermo Burillo-Putze; Santiago Mintegui; Pere Munne


Book ID
116192957
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
23 KB
Volume
22
Category
Article
ISSN
1532-8171

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Toxic Doses of Acetaminophen Suppress He
✍ Bernhard H. Lauterburg; Jerry R. Mitchell πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 563 KB

The effect of a toxic dose of acetaminophen on hepatic glutathione turnover was studied in fed and fasted rats. Following the administration of 1 g m per kg of acetaminophen, the fractional rate of glutathione turnover increased from 0.19 to 0.28 hr-' in fed rats and from 0.43 to 0.50 hr-' in rats f