Changes in neuronal activation in patients with bipolar disorder during performance of a working memory task
β Scribed by Caleb M Adler; Scott K Holland; Vince Schmithorst; Michael J Tuchfarber; Stephen M Strakowski
- Book ID
- 110905994
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 412 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1398-5647
No coin nor oath required. For personal study only.
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## Abstract Dysfunctions in prefrontal cortical networks are thought to underlie working memory (WM) impairments consistently observed in both subjects with bipolar disorder and schizophrenia. It remains unclear, however, whether patterns of WMβrelated hemodynamic responses are similar in bipolar a
## Abstract Recent evidence suggests that deficits of working memory may be a promising neurocognitive endophenotype of bipolar affective disorder. However, little is known about the neurobiological correlates of these deficits. The aim of this study was to determine possible pathophysiological tra